Accepted Posters List

In by admin

 Name Topic Title
Mrs. Elham YaaghubiOrganic Chemistry

A Class of Organosulfur Compounds Active Against HER2+ and EGFR+ Breast Cancer Cells

Mr. Mohit JaiswalBiochemistry / Chem Bio.

Cell-selective metabolic engineering for labeling GPI anchored proteins in cancer cells.

Mr. Shun TengOrganic Chemistry

Construction of Cross-layer Linked G-octamer via Conformational Control: Stable G-quadruplex in H-bond Competitive Solvent

Miss Rosemarie Martinez BorreroBiochemistry / Chem Bio.

Mechanistic studies of Mycobacterium tuberculosis Topoisomerase I inhibition by

endogenous toxin Rv1495

Alberto PerezComputational Chemistry

Protein and protein-protein structure prediction from evolutionary data

Mr. Arup MondalComputational Chemistry

Protein and protein-protein structure prediction from evolutionary data

Mrs. Yarixa Cintron-DiazAnalytical Chemistry

Protein screening of native brain sections using LESA-TIMS-MS

Dr. Baofu XuBiochemistry / Chem Bio.

Study on the Biosynthesis of Piperidine Ring Scaffold of Huperzine A

Mr. James DonnellyOrganic Chemistry

3, 4-Dihydroxyphenylacetaldehyde (DOPAL) is an important intermediate metabolite found in catecholamine neurotransmitter systems. As such, it has an important role in medicinal research directed toward the study of alcoholism, Alzheimer’s disease and Parkinson’s disease. Despite the immense biochemical significance of DOPAL, attempts to synthesize this compound in pure form has been met with grave difficulty. Various preparations of DOPAL have been reported, but the synthesis of this eight-carbon compound suffers from detailed procedures, physical isolation, full chemical characterization of the product/intermediates and extremely low overall product yield. These published methods also share one common problem, DOPAL is very unstable and is very difficult to isolate and work with. Therefore, considerable effort to produce DOPAL in a higher yield would be of interest. In an effort to mitigate these problems, we have directed our attention toward the synthesis of DOPAL using organobarium reagents. These novel reagents, fundamental to organic synthesis were utilized in the total synthesis of DOPAL. In addition, we also report the synthesis of the protected DOPAL via a Wittig reaction, but results of the hydrolysis/de-protection protocols have been interesting but unsatisfactory in the isolation of the free aldehyde. These studies may provide important insight on future drug action to combat PD and, when the scope of this research is expanded, may aid in the treatment of other neurodegenerative disorders.

Qingyu XingOrganic Chemistry

A Novel Design and Preparation of an Triazole-Based tridentate ligand

Ms. Bianca MitchellAnalytical Chemistry

A procedure for spectrophotometric quantification of 2,4-dinitrophenylhydrazine

Ms. Kaylie JanickiBiochemistry / Chem Bio.

A site-specific comparison of spherical and tubular capsid structure and assembly of Rous Sarcoma Virus

Nam VuComputational Chemistry

Adiabatic connection formalism for doubly-occupied configuration wavefunction as a new approach to capture dynamical correlation for strongly correlated system

Matthew KhouryPhysical Chemistry

Analysis of Methanol Cluster Aggregation via Mass Spectrometry Under Variable Pressure

Miss Nuzhat Nowshin OisheeBiochemistry / Chem Bio.

Atypical Protein Kinase-C inhibitor works synergistically with 5-Fluorouracil to reduce the viability of colorectal cancer cells.

 Name Topic Title